Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 12/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015261 | 0.84 | ADORA2A (0.46) | ADORA2AADORA2BPNPPDE4APDE4B | |
| SCHEMBL5667528 | 0.82 | ADORA2B (0.47) | ADORA2AADORA2BPNPPDE4APDE4B | |
| SCHEMBL48433 | 0.79 | ATAD2 (0.38) | ADORA2AADORA2BPNPPDE4APDE4B | |
| SCHEMBL16494562 | 0.79 | PNP (0.35) | PNP | |
| SCHEMBL7066008 | 0.79 | PNP (0.66) | ADORA2BPNPPDE4APDE4BPDE4C | |
| SCHEMBL29026230 | 0.77 | PNP (0.36) | PNP | |
| SCHEMBL11215532 | 0.76 | PNP (0.36) | ADORA2AADORA2BPNPADORA1 | |
| SCHEMBL7050396 | 0.76 | PNP (0.36) | PNP | |
| SCHEMBL17580687 | 0.76 | MEN1 (0.44) | PNPBLMPDE3A | |
| SCHEMBL6035390 | 0.76 | PNP (0.63) | ADORA2AADORA2BPNPPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060141523-A1 | Integrated method for PCR cleanup and oligonucleotide removal | APPLERA CORPORATION (US) | 2006-06-29 | — | — | US | disclosed |