Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235054 | 0.80 | MAPK1 (0.42) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL5972484 | 0.80 | KIF11 (0.43) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL6494684 | 0.79 | KCNN4 (0.41) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL8278933 | 0.78 | TAAR1 (0.54) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL812875 | 0.78 | CYP2C19 (0.48) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL28224667 | 0.78 | MAPK1 (0.46) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL2128913 | 0.78 | MAPK1 (0.37) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL7066960 | 0.76 | TSHR (0.44) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL14359797 | 0.76 | ALDH1A1 (0.44) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 | |
| SCHEMBL6293779 | 0.76 | KCNN4 (0.42) | MAPK1KCNN4ALOX15ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |