SCHEMBL706620

SCHEMBL706620

NC(N)Cc1cccc(S(=O)(=O)O)c1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.41
CYP1A2 P05177 1/20 0.38
FABP4 P15090 2/20 0.34
FABP3 P05413 1/20 0.34
FABP5 Q01469 1/20 0.34
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
KYNU Q16719 2/20 0.32
DAPK1 P53355 1/20 0.32
MYC P01106 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GAA P10253 1/20 0.31
CDK2 P24941 2/20 0.31
CCNA2 P20248 1/20 0.31
MAPK14 Q16539 1/20 0.31
NR4A1 P22736 1/20 0.30
GNG2 P59768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707080 0.85 MYC (0.41) TTRCYP1A2KYNUMYCTSHR
SCHEMBL2523958 0.77 GABRA1 (0.46) TTRCYP1A2FABP4FABP3FABP5
SCHEMBL8647427 0.76 TTR (0.40) TTRCYP1A2FABP4AURKAAURKB
SCHEMBL1269675 0.73 TTR (0.52) TTRCYP1A2FABP4AURKAAURKB
SCHEMBL2528805 0.73 TTR (0.38) TTRCYP1A2MYCHSD17B10SLC9A1
SCHEMBL7783766 0.72 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL7786031 0.72 PRSS1 (0.37) CYP1A2TSHRTDP1
SCHEMBL7787182 0.71 PRSS1 (0.36) CYP1A2ALDH1A1TSHRTDP1
SCHEMBL5184511 0.71 GABRA1 (0.46) TTRALDH1A1HSD17B10TDP1GAA
Hydrochloric Acid SCHEMBL628234 0.71 TTR (0.50) TTRCYP1A2FABP4AURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1944159-B1 NON-WOVEN FABRIC THAT ACTS AS AN INDICATOR GRUPO P I MABE SA DE C V (MX) 2014-03-26 EP claimed
US-8124546-B2 Non-woven fabric that acts as an indicator INDUSTRIAS MAQUIN S.A. DE C.V. (MX) 2012-02-28 US claimed
US-20080305700-A1 Non-Woven Fabric That Acts as an Indicator INDUSTRIAS MAQUIN S.A. DE C.V. (MX) 2008-12-11 US claimed
EP-1944159-A2 NON-WOVEN FABRIC THAT ACTS AS AN INDICATOR grupo P.I. Mabe, S.A. de C.V. (MX) 2008-07-16 EP claimed