Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.43 |
| ▸ | ESR1 | P03372 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130742 | 0.83 | AKT1 (0.42) | AKT1ESR2ESR1OPRM1PTPN1 | |
| SCHEMBL6130741 | 0.78 | CYP2D6 (0.40) | — | |
| SCHEMBL6767599 | 0.75 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL13551260 | 0.74 | DRD2 (0.37) | — | |
| SCHEMBL9983166 | 0.71 | AKR1B1 (0.38) | OPRM1OPRK1 | |
| SCHEMBL5546007 | 0.71 | MAPT (0.60) | AKT1ESR1PTPN1 | |
| SCHEMBL11009667 | 0.70 | TP53 (0.41) | AKT1ESR1OPRM1OPRD1OPRK1 | |
| SCHEMBL11005331 | 0.70 | TP53 (0.41) | AKT1ESR1OPRM1OPRD1OPRK1 | |
| SCHEMBL11005595 | 0.70 | TP53 (0.41) | AKT1ESR1OPRM1OPRD1OPRK1 | |
| SCHEMBL6130744 | 0.69 | PTPN1 (0.38) | ESR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314424-A1 | SEAMLESS SOFT CAPSULE PREPARATIONS CONTAINING DIHYDROBENZOFURAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-28 | — | — | EP | claimed |