Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068930 | 0.84 | AAK1 (0.42) | KMT2AMEN1GAA | |
| SCHEMBL28885280 | 0.83 | MAPT (0.61) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL7066317 | 0.79 | KMT2A (0.47) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL6500650 | 0.79 | MAPT (0.52) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL5562070 | 0.78 | KMT2A (0.50) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL8664998 | 0.78 | TDP1 (0.56) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL977967 | 0.77 | MEN1 (0.66) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL28773196 | 0.77 | KDM4E (0.58) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL14224679 | 0.75 | KDM4E (0.60) | RAB9AMAPTNPC1SMN1; SMN2KMT2A | |
| SCHEMBL7065211 | 0.75 | IDO1 (0.39) | MAPTSMN1; SMN2PKML3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |