Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064560 | 0.89 | HRH3 (0.39) | HRH3HSD17B10HDAC1HDAC8HDAC6 | |
| SCHEMBL7068046 | 0.83 | HDAC1 (0.39) | HRH3HTTNPSR1HDAC1HDAC8 | |
| SCHEMBL6501452 | 0.82 | IDO1 (0.41) | IDO1HRH3ALDH1A1HPGDTP53 | |
| SCHEMBL7065219 | 0.82 | IDO1 (0.38) | IDO1ALDH1A1HPGDTP53HTT | |
| SCHEMBL7070085 | 0.81 | MAPT (0.36) | ALDH1A1TP53HTTMAPTNPSR1 | |
| SCHEMBL7160232 | 0.78 | HDAC1 (0.42) | HRH3HPGDNPSR1HDAC1HDAC8 | |
| SCHEMBL7068930 | 0.78 | AAK1 (0.42) | HDAC1MEN1KMT2AGAAPPARG | |
| SCHEMBL7066309 | 0.75 | RAB9A (0.47) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7129648 | 0.73 | LMNA (0.37) | HRH3HTTHSD17B10HDAC1HDAC8 | |
| SCHEMBL6487724 | 0.71 | HDAC1 (0.39) | HRH3ALDH1A1HPGDMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |