Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 9/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072731 | 0.97 | S1PR1 (0.46) | KDM4EGAAL3MBTL1S1PR1S1PR3 | |
| SCHEMBL62489 | 0.92 | NPC1 (0.46) | ALDH1A1MAPTDHODHTSHR | |
| SCHEMBL3852129 | 0.87 | ALDH1A1 (0.45) | KDM4EGAAALDH1A1MAPTDHODH | |
| SCHEMBL5046716 | 0.84 | DHODH (0.58) | KDM4EGAAALDH1A1MAPTDHODH | |
| SCHEMBL395325 | 0.84 | DHODH (0.46) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3883132 | 0.83 | DHODH (0.44) | KDM4EALDH1A1MAPTL3MBTL1DHODH | |
| SCHEMBL7066714 | 0.83 | DHODH (0.60) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL436620 | 0.83 | DHODH (0.44) | KDM4EGAAALDH1A1MAPTS1PR1 | |
| SCHEMBL846105 | 0.83 | MAPT (0.45) | KDM4EGAAALDH1A1MAPTDHODH | |
| SCHEMBL11330329 | 0.82 | KDM4E (0.43) | KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0895776-B1 | Cosmetic light-screening composition | HOFFMANN LA ROCHE (CH) | 2003-06-11 | — | — | EP | disclosed |
| US-6069170-A | 2-(4-ALKOXY-ANILINOMETHYLENE)-PROPANEDIOIC ACID DIESTER USED AS SUNSCREEN AGENT | ROCHE VITAMINS INC. (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0895776-A2 | Cosmetic light-screening composition | F. HOFFMANN-LA ROCHE AG (CH) | 1999-02-10 | — | — | EP | disclosed |