SCHEMBL62489

SCHEMBL62489

CCOc1ccc(NC=C(C(=O)O)C(=O)OC(C)CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
PKM P14618 1/20 0.46
ALDH1A1 P00352 2/20 0.46
DHODH Q02127 1/20 0.46
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 2/20 0.41
EGFR P00533 1/20 0.41
TSHR P16473 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066341 0.92 KDM4E (0.44) ALDH1A1DHODHMAPTTSHR
SCHEMBL3852129 0.90 ALDH1A1 (0.45) NPC1RAB9APKMALDH1A1DHODH
SCHEMBL7072731 0.89 S1PR1 (0.46) TSHR
SCHEMBL5046716 0.87 DHODH (0.58) RAB9AALDH1A1DHODHKMT2APOLB
SCHEMBL395325 0.87 DHODH (0.46) NPC1RAB9APKMALDH1A1DHODH
SCHEMBL3883132 0.86 DHODH (0.44) NPC1RAB9APKMALDH1A1DHODH
SCHEMBL436620 0.86 DHODH (0.44) NPC1RAB9AALDH1A1DHODHKMT2A
SCHEMBL846105 0.86 MAPT (0.45) ALDH1A1DHODHKMT2AMEN1LMNA
SCHEMBL63413 0.85 NPC1 (0.56) NPC1RAB9APKMALDH1A1DHODH
SCHEMBL7071412 0.84 DHODH (0.65) NPC1RAB9APKMALDH1A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9402793-B2 Use of UV-filters to stabilize resveratrol in topical cosmetic compositions DSM IP ASSETS B.V. (NL) 2016-08-02 US claimed
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER DSM IP ASSETS B.V. (NL) 2015-06-25 US claimed
US-20130324616-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP ASSETS B.V. (NL) 2013-12-05 US claimed
US-20130315848-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2013-11-28 US claimed
EP-2642973-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP Assets B.V. (NL) 2013-10-02 EP claimed
EP-2642972-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP Assets B.V. (NL) 2013-10-02 EP claimed
WO-2012069363-A1 USE OF UV-FILTERS TO STABILIZE RESVERATROL IN TOPICAL COSMETIC COMPOSITIONS DSM IP ASSETS B.V. (NL) 2012-05-31 WO claimed
WO-2012069362-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2012-05-31 WO claimed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 WO claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
EP-3709956-B1 COSMETIC OR DERMATOLOGICAL COMPOSITIONS DSM IP ASSETS BV (NL) 2024-10-23 EP disclosed
US-20220160649-A1 PHARMACEUTICAL COMPOSITION DOBMEYER RITA (CH) 2022-05-26 US disclosed
EP-3941449-A1 PHARMACEUTICAL COMPOSITION Dobmeyer, Rita (CH) 2022-01-26 EP disclosed
US-11207256-B2 Method for solubilizing poorly water-soluble cosmetic agents ATHENION AG (CH) 2021-12-28 US disclosed
EP-2032115-B1 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS BV (NL) 2021-07-21 EP disclosed
WO-2002055029-A2 HAIR PROTECTION COMPOSITIONS ROCHE VITAMINS AG (CH) 2002-07-18 WO disclosed
US-6165451-A Cosmetic light screening composition ROCHE VITAMINS INC. (US) 2000-12-26 US disclosed
EP-1025836-A1 Cosmetic light screening composition F. HOFFMANN-LA ROCHE AG (CH) 2000-08-09 EP disclosed
US-6069170-A 2-(4-ALKOXY-ANILINOMETHYLENE)-PROPANEDIOIC ACID DIESTER USED AS SUNSCREEN AGENT ROCHE VITAMINS INC. (US) 2000-05-30 US disclosed
EP-0895776-A2 Cosmetic light-screening composition F. HOFFMANN-LA ROCHE AG (CH) 1999-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160649-A1 PHARMACEUTICAL COMPOSITION FGF23, FGFR3, FGFR2 NPC1 1242/4885RAB9A 1462/4885PKM 3494/4885
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER ERCC4, ERCC2, ERCC1 NPC1 3188/4885RAB9A 2804/4885PKM 3016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.