Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407846 | 0.80 | TSHR (0.37) | TSHRLMNAHCAR2 | |
| SCHEMBL7066356 | 0.80 | TSHR (0.37) | TSHRLMNAHCAR2 | |
| SCHEMBL6064146 | 0.79 | LMNA (0.42) | TSHRLMNAHCAR2 | |
| SCHEMBL15878440 | 0.79 | TSHR (0.40) | TSHRLMNAHCAR2 | |
| SCHEMBL18075114 | 0.78 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL18075113 | 0.78 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL9065139 | 0.76 | CA1 (0.39) | TSHR | |
| SCHEMBL6063160 | 0.76 | LMNA (0.48) | TSHRLMNA | |
| SCHEMBL7642736 | 0.75 | FAAH (0.37) | TSHRLMNA | |
| SCHEMBL9065703 | 0.74 | TDP1 (0.44) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | claimed |
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |