Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067156 | 0.95 | FKBP1A (0.44) | FKBP1ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7062864 | 0.90 | FKBP1A (0.40) | FKBP1ATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL7060882 | 0.89 | CHRM2 (0.47) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7066664 | 0.88 | FKBP1A (0.43) | FKBP1ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7066798 | 0.85 | ALDH1A1 (0.39) | FKBP1ATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL7066206 | 0.85 | FKBP1A (0.40) | FKBP1ATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL7062141 | 0.84 | FKBP1A (0.43) | FKBP1A | |
| SCHEMBL7064527 | 0.84 | CHRM2 (0.44) | FKBP1ATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL7066644 | 0.81 | ALDH1A1 (0.43) | FKBP1ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7067185 | 0.80 | TSHR (0.58) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |