Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066644 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TDP1L3MBTL1CNR1MAPT | |
| SCHEMBL7066156 | 0.87 | MAPT (0.47) | ALDH1A1MAPTTSHRMAPK1RECQL | |
| SCHEMBL7066432 | 0.85 | FKBP1A (0.43) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7064487 | 0.83 | FKBP1A (0.44) | L3MBTL1CNR1CNR2CHRM2CHRM4 | |
| SCHEMBL6233904 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL7066175 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL6235377 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2TSHR | |
| SCHEMBL7067156 | 0.81 | FKBP1A (0.44) | ALDH1A1L3MBTL1FKBP1ATSHR | |
| SCHEMBL7064598 | 0.80 | FKBP1A (0.43) | L3MBTL1CNR1CNR2FKBP1A | |
| SCHEMBL7060882 | 0.78 | CHRM2 (0.47) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |