Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291476 | 0.78 | MEN1 (0.49) | CXCR3 | |
| SCHEMBL12536501 | 0.74 | CXCR3 (0.48) | CXCR3 | |
| SCHEMBL16152253 | 0.73 | CXCR3 (0.58) | CXCR3 | |
| SCHEMBL12829869 | 0.72 | CXCR3 (0.56) | CXCR3 | |
| SCHEMBL14622633 | 0.72 | CXCR3 (0.51) | CXCR3 | |
| SCHEMBL13633713 | 0.70 | CXCR3 (0.48) | CXCR3 | |
| SCHEMBL12464100 | 0.69 | CXCR3 (0.67) | CXCR3 | |
| SCHEMBL12463876 | 0.69 | PDE10A (0.53) | CXCR3 | |
| SCHEMBL12830455 | 0.68 | CXCR3 (0.56) | CXCR3 | |
| SCHEMBL12830456 | 0.68 | CXCR3 (0.63) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220356-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220356-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | CXCR3 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.