Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066580 | 1.00 | TP53 (0.49) | TP53L3MBTL1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11198165 | 0.76 | CES2 (0.50) | TP53L3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL11198155 | 0.76 | CES2 (0.50) | TP53L3MBTL1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL9821675 | 0.74 | TP53 (0.66) | TP53L3MBTL1ALDH1A1KMT2AMAPT | |
| SCHEMBL30421622 | 0.74 | TP53 (0.66) | TP53L3MBTL1ALDH1A1KMT2AMAPT | |
| SCHEMBL7068206 | 0.73 | TP53 (0.44) | TP53L3MBTL1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7068209 | 0.73 | TP53 (0.44) | TP53L3MBTL1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8032364 | 0.73 | NR4A1 (0.41) | ALDH1A1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL8032369 | 0.73 | NR4A1 (0.41) | ALDH1A1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL8631890 | 0.71 | CES2 (0.45) | TP53L3MBTL1ALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996614-B1 | ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2003-06-11 | — | — | EP | disclosed |
| US-6187944-B1 | A PHENYL ACRYLONITRILE COMPOUNDS USEFUL AS ACTIVE INGREDIENTS OF AN INSECTICIDE, A MITICIDE, A NEMATICIDE, A SOIL PESTICIDE, A FUNGICIDE AND A MARINE ANTIFOULING AGENT | ISHIHARA SANGYO KAISHA LTD. (JP) | 2001-02-13 | — | — | US | disclosed |