Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421622 | 1.00 | TP53 (0.66) | TP53L3MBTL1ALOX15LMNAMAPT | |
| Propionic Acid SCHEMBL9592677 | 0.89 | ALOX15 (0.58) | TP53L3MBTL1ALOX15LMNAMAPT | |
| SCHEMBL9148337 | 0.86 | LMNA (0.85) | TP53L3MBTL1ALOX15LMNAMAPT | |
| SCHEMBL8900631 | 0.81 | TP53 (0.60) | TP53L3MBTL1ALOX15LMNAMAPT | |
| SCHEMBL11755917 | 0.81 | SMN1; SMN2 (0.68) | L3MBTL1ALOX15LMNAMAPTALDH1A1 | |
| SCHEMBL7201699 | 0.80 | L3MBTL1 (0.68) | TP53L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL15979664 | 0.80 | ALDH1A1 (0.68) | TP53L3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL10618289 | 0.79 | ALOX15 (0.68) | L3MBTL1ALOX15LMNAMAPTALDH1A1 | |
| SCHEMBL3859942 | 0.79 | ALOX15 (1.00) | TP53ALOX15LMNAMAPTALDH1A1 | |
| SCHEMBL24105612 | 0.78 | ALOX15 (0.49) | TP53L3MBTL1ALOX15LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187470-B1 | HERBICIDAL HETEROARYLBENZENE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4906283-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |
| US-4759790-A | Plant growth regulator | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-26 | — | — | US | disclosed |
| US-4690705-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0187470-A2 | Herbicidal heteroarylbenzene sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4029808-A | Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators | C.E.R.P.H.A. A FRENCH SOCIETY ORGANISED UNDER THE LAWS OF FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |