Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068206 | 1.00 | TP53 (0.44) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL7066579 | 0.73 | TP53 (0.49) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL7066580 | 0.73 | TP53 (0.49) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050259 | 0.72 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL18050258 | 0.72 | MAPT (0.59) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL9821675 | 0.70 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL30421622 | 0.70 | TP53 (0.66) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| Propionic Acid SCHEMBL9592677 | 0.67 | ALOX15 (0.58) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL11198165 | 0.66 | CES2 (0.50) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL11198155 | 0.66 | CES2 (0.50) | TP53L3MBTL1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11158137-A | — | — | None | — | — | JP | disclosed |
| EP-0996614-B1 | ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2003-06-11 | — | — | EP | disclosed |
| US-6187944-B1 | A PHENYL ACRYLONITRILE COMPOUNDS USEFUL AS ACTIVE INGREDIENTS OF AN INSECTICIDE, A MITICIDE, A NEMATICIDE, A SOIL PESTICIDE, A FUNGICIDE AND A MARINE ANTIFOULING AGENT | ISHIHARA SANGYO KAISHA LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| JP-H11158137-A | ACRYLONITRILE COMPOUND, PRODUCTION THEREOF AND PEST-CONTROLLING AGENT CONTAINING THE SAME | ISHIHARA SANGYO KAISHA LTD | 1999-06-15 | — | — | JP | disclosed |