Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971345 | 0.93 | NAAA (0.48) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL7067966 | 0.93 | ALDH1A1 (0.47) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL7973579 | 0.90 | NAAA (0.46) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811481 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811482 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811669 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811520 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811516 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811449 | 0.89 | NAAA (0.52) | NAAAEPHX1ESR1AKR1C4AKR1C3 | |
| SCHEMBL21811608 | 0.87 | NAAA (0.48) | NAAAEPHX1ESR1AKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |