Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7066889 | 0.93 | NAAA (0.48) | ESR1TSHRHCAR2NAAAAKR1C4 | |
| SCHEMBL7976245 | 0.92 | ALDH1A1 (0.47) | ALDH1A1ATMESR1TSHRHPGD | |
| SCHEMBL2865591 | 0.90 | ALDH1A1 (0.52) | ALDH1A1ATMESR1TSHRHPGD | |
| SCHEMBL7976354 | 0.89 | ALDH1A1 (0.44) | ALDH1A1ATMESR1TSHRHPGD | |
| SCHEMBL2868296 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ATMESR1TSHRHPGD | |
| SCHEMBL21811494 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ATMESR1TSHRHPGD | |
| SCHEMBL7971345 | 0.85 | NAAA (0.48) | ALDH1A1ESR1TSHRHCAR2NAAA | |
| SCHEMBL8027706 | 0.85 | NAAA (0.47) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL21811608 | 0.82 | NAAA (0.48) | ALDH1A1ATMESR1TSHRHCAR2 | |
| SCHEMBL7973579 | 0.82 | NAAA (0.46) | ALDH1A1ESR1TSHRHCAR2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827954-B1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL CO (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6114543-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5880291-A | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0827954-A1 | Process for producing optically active azetidine-2-carboxylic acid | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-03-11 | — | — | EP | disclosed |