Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1808553 | 0.93 | TSHR (0.45) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL7062178 | 0.89 | TSHR (0.40) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL3413337 | 0.85 | THRB (0.45) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL7065851 | 0.83 | THRB (0.40) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL1805856 | 0.82 | TSHR (0.44) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL5704237 | 0.81 | THRB (0.49) | THRBTSHRTHRAKMT2APOLB | |
| SCHEMBL10604787 | 0.78 | TSHR (0.46) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL7066709 | 0.78 | MEN1 (0.43) | THRBTSHRTHRAMEN1KMT2A | |
| SCHEMBL7067871 | 0.78 | MEN1 (0.40) | THRBTHRAMEN1KMT2APOLB | |
| SCHEMBL10630301 | 0.78 | THRB (0.42) | THRBTSHRTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | claimed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | claimed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | claimed |
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |