Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 7/20 | 0.35 |
| ▸ | THRA | P10827 | 6/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067871 | 0.88 | MEN1 (0.40) | MEN1KMT2AGABRA1GABRB1THRB | |
| SCHEMBL7067636 | 0.82 | THRB (0.38) | MEN1KMT2AGABRA1GABRB1THRB | |
| SCHEMBL7061577 | 0.81 | GABRA1 (0.35) | KMT2AGABRA1GABRB1THRBTHRA | |
| SCHEMBL1534879 | 0.81 | THRA (0.35) | MEN1KMT2AGABRA1GABRB1THRB | |
| SCHEMBL4683298 | 0.80 | THRA (0.33) | MEN1KMT2AGABRA1GABRB1THRB | |
| SCHEMBL7066275 | 0.80 | GABRA1 (0.38) | GABRA1GABRB1THRBTHRAALOX15 | |
| SCHEMBL7066995 | 0.79 | GABRA1 (0.33) | KMT2AGABRA1GABRB1ALOX15ALOX12 | |
| SCHEMBL6285005 | 0.78 | MEN1 (0.55) | MEN1KMT2AMCHR1THRBTHRA | |
| SCHEMBL7065851 | 0.78 | THRB (0.40) | MEN1KMT2ATHRBTHRAMCL1 | |
| SCHEMBL7066987 | 0.78 | THRB (0.38) | MEN1KMT2ATHRBTHRAMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109776-B1 | BROMINATED MATERIALS | MINNESOTA MINING & MFG (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6533959-B2 | Formed from monomers such as 2-(4,6-dibromo-2-isopropyl phenoxy)ethyl acrylate; high index of refraction, useful to control flow and intensity of light | 3M INNOVATIVE PROPERTIES COMPANY | 2003-03-18 | — | — | US | disclosed |
| US-20020123590-A1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-09-05 | — | — | US | disclosed |
| US-6359170-B1 | Brominated materials | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6261700-B1 | HARD COATING | 3M INNOVATIVE PROPERTIES COMPANY | 2001-07-17 | — | — | US | disclosed |
| EP-1109776-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1105430-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000014050-A1 | BROMINATED MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-03-16 | — | — | WO | disclosed |
| WO-2000006622-A1 | CERAMER CONTAINING A BROMINATED POLYMER AND INORGANIC OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123590-A1 | Brominated materials | PBRM1, TUBB3, TUBB | MEN1 2240/4885KMT2A 1043/4885MCHR1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.