SCHEMBL7067294

SCHEMBL7067294

Cc1nn(-c2ccc(Cl)cc2)c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
POLB P06746 3/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
OPRM1 P35372 1/20 0.41
PTGS2 P35354 1/20 0.41
ADORA3 P0DMS8 1/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CA9 Q16790 1/20 0.40
GRM1 Q13255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23565228 0.82 ABHD16A (0.44) SMN1; SMN2NPC1RAB9AMEN1KMT2A
SCHEMBL13114729 0.82 NPC1 (0.47) GAASMN1; SMN2NPC1RAB9AMEN1
SCHEMBL3170478 0.81 MAPK1 (0.47) SMN1; SMN2RAB9AMEN1KMT2AADORA3
SCHEMBL14276774 0.81 HPGD (0.48) GAASMN1; SMN2MEN1KMT2AMAPT
SCHEMBL5973251 0.78 CDK4 (0.53) L3MBTL1OPRM1LMNAALDH1A1HTT
SCHEMBL29833592 0.78 CDK4 (0.53) L3MBTL1OPRM1LMNAALDH1A1HTT
SCHEMBL3404607 0.78 ATM (0.62) SMN1; SMN2KMT2ALMNA
SCHEMBL10338166 0.78 KMT2A (0.42) GAASMN1; SMN2NPC1RAB9AMEN1
SCHEMBL8721162 0.74 L3MBTL1 (0.56) GAAMEN1KMT2APOLBMAPT
SCHEMBL30782807 0.74 CDK4 (0.42) NPC1RAB9AOPRM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798177-A In the sulfenamide Process for the preparation of intermediates 宁夏格瑞精细化工有限公司 2025-04-11 CN disclosed
CN-117402122-A Preparation method of sulfentrazone and triazolone-oxadiazon triazolinone intermediate 宁夏格瑞精细化工有限公司 2024-01-16 CN disclosed
CN-115850195-A Synthetic method of sulfentrazone intermediate 宁夏格瑞精细化工有限公司 2023-03-28 CN disclosed
CN-113402472-B Synthetic method of sulfentrazone intermediate 山东潍坊润丰化工股份有限公司 2022-09-13 CN disclosed
CN-113402472-A Synthetic method of sulfentrazone intermediate 山东潍坊润丰化工股份有限公司 2021-09-17 CN disclosed
US-8669371-B2 Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones TAGROS CHEMICALS INDIA PVT LTD (IN) 2014-03-11 US disclosed
US-20130072689-A1 Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones TAGROS CHEMICALS INDIA, LTD. (IN) 2013-03-21 US disclosed
EP-1115711-B1 REGIOSELECTIVE FLUORINATION OF PHENYL-SUBSTITUTED TRIAZOLINONES FMC CORP (US) 2003-06-04 EP disclosed
EP-1115711-A1 REGIOSELECTIVE FLUORINATION OF PHENYL-SUBSTITUTED TRIAZOLINONES FMC CORPORATION (US) 2001-07-18 EP disclosed
US-6218545-B1 Regioselective fluorination of phenyl-substituted triazolinones FMC CORPORATION 2001-04-17 US disclosed
US-5468868-A Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one FMC CORPORATION (US) 1995-11-21 US disclosed
US-5466820-A Fungicides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-11-14 US disclosed
US-5440045-A Triazolinone ring formation in tert-butanol FMC CORPORATION (US) 1995-08-08 US disclosed
EP-0640076-A4 TRIAZOLINONE RING FORMATION IN TERT-BUTANOL. FMC CORP (US) 1995-04-12 EP disclosed
EP-0640076-A1 TRIAZOLINONE RING FORMATION IN TERT-BUTANOL FMC CORPORATION (US) 1995-03-01 EP disclosed
US-5371101-A Fungicides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-12-06 US disclosed
WO-1993023382-A1 TRIAZOLINONE RING FORMATION IN TERT-BUTANOL FMC CORPORATION (US) 1993-11-25 WO disclosed
EP-0567982-A1 Azole compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1993-11-03 EP disclosed
US-5256793-A Triazolinone ring formation in tert-butanol FMC CORPORATION (US) 1993-10-26 US disclosed
US-4980480-A Production of triazolinones FMC CORPORATION (US) 1990-12-25 US disclosed