Sugi Predict

Sugi Predict / Compounds / SCHEMBL3170478

SCHEMBL3170478

SCHEMBL3170478

Cc1nn(-c2ccccc2)c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 3/20 0.47
▸ HPGD P15428 3/20 0.47
▸ ADORA3 P0DMS8 3/20 0.46
▸ HSD17B10 Q99714 3/20 0.46
▸ KDM4E B2RXH2 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ RAB9A P51151 1/20 0.44
▸ GABRA1 P14867 1/20 0.43
▸ GABRG2 P18507 1/20 0.43
▸ GABRB3 P28472 1/20 0.43
▸ GABRA3 P34903 1/20 0.43
▸ GABRA2 P47869 1/20 0.43
▸ HIF1A Q16665 1/20 0.42
▸ PARP1 P09874 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ HTT P42858 2/20 0.41
▸ TNF P01375 1/20 0.41
▸ ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15871236 0.81 HPGD (0.56) MAPK1HPGDADORA3HSD17B10KDM4E
SCHEMBL13114729 0.81 NPC1 (0.47) HPGDHSD17B10KDM4EALDH1A1RAB9A
SCHEMBL23565228 0.81 ABHD16A (0.44) ADORA3ALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL7067294 0.81 GAA (0.47) ADORA3ALDH1A1RAB9ASMN1; SMN2HTT
SCHEMBL14276774 0.81 HPGD (0.48) MAPK1HPGDKDM4EALDH1A1SMN1; SMN2
SCHEMBL2730519 0.81 AR (0.44) HPGDHSD17B10KDM4EALDH1A1HTT
SCHEMBL9052724 0.78 KMT2A (0.43) ADORA3HSD17B10KDM4EALDH1A1HTT
SCHEMBL9966144 0.78 ALDH1A1 (0.44) MAPK1HPGDADORA3HSD17B10KDM4E
SCHEMBL3404607 0.78 ATM (0.62) KDM4EHIF1ASMN1; SMN2ATMLMNA
SCHEMBL31585569 0.77 ADORA3 (0.43) MAPK1HPGDADORA3HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112225705-B Preparation method of 3-methyl-1-phenyl-1H-1,2, 4-triazole-5 (4H) -ketone 湖南海利常德农药化工有限公司 2022-06-07 — — CN claimed
CN-112225705-A Preparation method of 3-methyl-1-phenyl-1H-1,2, 4-triazole-5 (4H) -ketone 湖南海利常德农药化工有限公司 2021-01-15 — — CN claimed
US-8669371-B2 Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones TAGROS CHEMICALS INDIA PVT LTD (IN) 2014-03-11 — — US claimed
US-20130072689-A1 Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones TAGROS CHEMICALS INDIA, LTD. (IN) 2013-03-21 — — US claimed
US-5756755-A Difluoromethylation of 4,5-dihydro-1-phenyl-3-methyl-1,2,4-triazol-5(1H)-ones with glymes as solvents FMC CORPORATION (US) 1998-05-26 — — US claimed
WO-1997003972-A1 DIFLUOROMETHYLATION OF A PHENYL TRIAZOLINONE FMC CORPORATION (US) 1997-02-06 — — WO claimed
US-5468868-A Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one FMC CORPORATION (US) 1995-11-21 — — US claimed
US-5438149-A Reacting with chlorodifluoromethane and potassium carbonate while heating in solvent of dimethylformamide, 1-methyl-2-pyrrolidone or N,N-dimethylacetamide FMC CORPORATION (US) 1995-08-01 — — US claimed
CN-121318865-A Method for efficiently and cleanly preparing 3-methyl-1-phenyl-1, 2, 4-triazolin-5-one 宁夏格瑞精细化工有限公司 2026-01-13 — — CN disclosed
CN-121318865-A Method for efficiently and cleanly preparing 3-methyl-1-phenyl-1, 2, 4-triazolin-5-one 宁夏格瑞精细化工有限公司 2026-01-13 — — CN disclosed
US-20250331521-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE NIHON NOHYAKU CO., LTD. (JP) 2025-10-30 — — US disclosed
EP-4480950-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING Nihon Nohyaku Co., Ltd. (JP) 2024-12-25 — — EP disclosed
CN-118891254-A Nitrogen-containing heterocyclic compound having oxime group, agrohorticultural herbicide containing the same, and method of using the same 日本农药株式会社 2024-11-01 — — CN disclosed
CN-117402122-A Preparation method of sulfentrazone and triazolone-oxadiazon triazolinone intermediate 宁夏格瑞精细化工有限公司 2024-01-16 — — CN disclosed
WO-1993023382-A1 TRIAZOLINONE RING FORMATION IN TERT-BUTANOL FMC CORPORATION (US) 1993-11-25 — — WO disclosed
US-5256793-A Triazolinone ring formation in tert-butanol FMC CORPORATION (US) 1993-10-26 — — US disclosed
EP-0490936-A4 PRODUCTION OF TRIAZOLINONES — 1992-10-14 — — EP disclosed
EP-0490936-A1 PRODUCTION OF TRIAZOLINONES. FMC CORP (US) 1992-06-24 — — EP disclosed
WO-1991003470-A1 PRODUCTION OF TRIAZOLINONES FMC CORPORATION (US) 1991-03-21 — — WO disclosed
US-4980480-A Production of triazolinones FMC CORPORATION (US) 1990-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250331521-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE DDT, HDHD5, HAAO MAPK1 399/4885HPGD 232/4885ADORA3 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.