Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001531 | 0.85 | TSHR (0.42) | KMT2AMEN1SMN1; SMN2GAANPC1 | |
| SCHEMBL28114764 | 0.84 | L3MBTL1 (0.35) | KMT2AMEN1L3MBTL1POLBADORA3 | |
| SCHEMBL10274594 | 0.83 | ADORA3 (0.47) | SMN1; SMN2L3MBTL1POLBADORA3ALDH1A1 | |
| SCHEMBL7067294 | 0.78 | GAA (0.47) | KMT2AMEN1SMN1; SMN2GAANPC1 | |
| SCHEMBL28414462 | 0.73 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29001509 | 0.71 | HCAR1 (0.42) | ADORA3ALDH1A1TSHRLMNACCNE1 | |
| SCHEMBL29001520 | 0.70 | TSHR (0.40) | KMT2AMEN1SMN1; SMN2GAAMAPT | |
| SCHEMBL7654423 | 0.70 | ALDH1A1 (0.47) | KMT2AMEN1SMN1; SMN2GAANPC1 | |
| SCHEMBL9033166 | 0.69 | PARP1 (0.48) | SMN1; SMN2RAB9AMAPTL3MBTL1ADORA3 | |
| SCHEMBL7909905 | 0.68 | KMT2A (0.58) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2015069-A | — | — | None | — | — | JP | disclosed |
| JP-H0215069-A | DELTA2-1,2,4-TRIAZOLIN-5-ONE DERIVATIVE, ITS PRODUCTION AND ANTI-INFLAMMATORY AGENT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | KAKEN PHARMACEUT CO LTD | 1990-01-18 | — | — | JP | disclosed |