Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187620 | 0.87 | TDP1 (0.39) | HTTALDH1A1MAPTTSHRCYP3A4 | |
| SCHEMBL8780860 | 0.82 | TDP1 (0.43) | KDM4EALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL348351 | 0.82 | KDM4E (0.39) | HTTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5000276 | 0.79 | HTR1A (0.39) | MEN1KMT2AOPRM1 | |
| SCHEMBL5003993 | 0.76 | MEN1 (0.46) | HTTMEN1KMT2AMAPTTDP1 | |
| SCHEMBL8100023 | 0.76 | LTA4H (0.36) | TSHRLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL5000404 | 0.75 | KMT2A (0.47) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8652282 | 0.74 | KCNH2 (0.41) | HTTKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL5003760 | 0.74 | KCNH2 (0.41) | HTTKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL8097672 | 0.73 | LTA4H (0.35) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944638-B1 | CIS-BRIDGED METAL COMPLEXES | BASF AG (DE) | 2003-06-11 | — | — | EP | disclosed |
| EP-0944638-A1 | CIS-BRIDGED METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025939-A1 | CIS-BRIDGED METAL COMPLEXES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |