Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5003993 | 0.88 | MEN1 (0.46) | HTR1ADRD3OPRM1DRD2OPRD1 | |
| SCHEMBL9187620 | 0.87 | TDP1 (0.39) | HTR1ADRD3OPRM1KCNH2CHRM2 | |
| SCHEMBL15984647 | 0.85 | KCNH2 (0.51) | HTR1ADRD3OPRM1DRD2OPRD1 | |
| SCHEMBL8652282 | 0.83 | KCNH2 (0.41) | HTR1ADRD3OPRM1DRD2OPRK1 | |
| SCHEMBL5003760 | 0.83 | KCNH2 (0.41) | HTR1ADRD3OPRM1DRD2OPRK1 | |
| SCHEMBL8780860 | 0.82 | TDP1 (0.43) | — | |
| SCHEMBL5039661 | 0.82 | HTR1A (0.42) | HTR1ADRD3OPRM1DRD2OPRD1 | |
| SCHEMBL18213635 | 0.82 | HTR1A (0.42) | HTR1ADRD3OPRM1DRD2OPRD1 | |
| SCHEMBL7067524 | 0.79 | HTT (0.41) | OPRM1MEN1KMT2A | |
| SCHEMBL5000404 | 0.79 | KMT2A (0.47) | RAB9ATP53CHRM2CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267868-A1 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | NIHON MEDI-PHYSICS, CO., LTD. (JP) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267868-A1 | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex | PNP, SHBG, NPPA | HTR1A 663/4885DRD3 3669/4885OPRM1 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.