Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067552 | 0.92 | HTT (0.37) | HTTLMNA | |
| SCHEMBL27605067 | 0.79 | TSHR (0.46) | TSHRPGDHTTALDH1A1 | |
| SCHEMBL94759 | 0.77 | TSHR (0.48) | TSHRPGDHTTALDH1A1 | |
| SCHEMBL9149983 | 0.77 | TSHR (0.48) | TSHRPGDHTT | |
| Methylmalonic Acid SCHEMBL28186299 | 0.76 | — | — | |
| SCHEMBL181730 | 0.75 | MIF (0.32) | LMNA | |
| SCHEMBL7035397 | 0.75 | TSHR (0.46) | TSHRPGDHTTALDH1A1 | |
| SCHEMBL27625179 | 0.75 | TSHR (0.46) | TSHRPGDHTTALDH1A1 | |
| SCHEMBL8972472 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1LMNA | |
| SCHEMBL23069532 | 0.74 | ALDH1A1 (0.54) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317267-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | Targacept, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1311265-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | Targacept, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002005801-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002005798-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |