Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067555 | 0.92 | TSHR (0.39) | HTTLMNA | |
| SCHEMBL181730 | 0.82 | MIF (0.32) | MIFLMNA | |
| SCHEMBL385886 | 0.80 | ALDH1A1 (0.41) | MIFLMNA | |
| SCHEMBL6970029 | 0.78 | CA2 (0.38) | MIF | |
| SCHEMBL165589 | 0.75 | NAAA (0.39) | HTTLMNA | |
| Methylmalonic Acid SCHEMBL28186299 | 0.74 | — | — | |
| SCHEMBL27475793 | 0.73 | HMGCR (0.36) | MIFLMNA | |
| SCHEMBL182236 | 0.73 | ALDH1A1 (0.42) | MIFLMNA | |
| SCHEMBL2182293 | 0.73 | ALDH1A1 (0.45) | HTTMIFLMNA | |
| SCHEMBL28992512 | 0.72 | MMP8 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317267-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | Targacept, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1311265-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | Targacept, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002005801-A2 | COMPOSITIONS CONTAINING DIACYLTARTARIC SALTS OF (E)-METANICOTINE | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002005798-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS | TARGACEPT, INC. (US) | 2002-01-24 | — | — | WO | disclosed |