Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199723 | 0.66 | TSHR (0.37) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 | |
| SCHEMBL5690313 | 0.66 | BRD4 (0.38) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 | |
| SCHEMBL8464420 | 0.66 | ADRB2 (0.36) | KDM4EHTTLMNATP53RAB9A | |
| SCHEMBL5086245 | 0.65 | PTAFR (0.34) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 | |
| SCHEMBL5953635 | 0.65 | SIGMAR1 (0.33) | HTTLMNA | |
| Hydrochloric Acid SCHEMBL5697214 | 0.65 | KIF11 (0.37) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 | |
| SCHEMBL6231893 | 0.64 | PTAFR (0.37) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 | |
| SCHEMBL24522126 | 0.63 | TSHR (0.48) | BRD4CREBBPKIF11SMN1; SMN2KDM4E | |
| SCHEMBL25710543 | 0.63 | KIF11 (0.45) | BRD4CREBBPKIF11SMN1; SMN2KDM4E | |
| SCHEMBL6012037 | 0.63 | TSHR (0.36) | BRD4CREBBPKIF11PTAFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | Basell Polypropylen GmbH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018397-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYPROPYLEN GMBH (DE) | 2002-03-07 | — | — | WO | disclosed |