SCHEMBL6807428

SCHEMBL6807428

CC(C)(C)OC(=O)N(CCc1ccc(N)cc1)S(=O)(=O)c1cccc(F)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 3/20 0.41
TAS2R14 Q9NYV8 3/20 0.38
ADRB3 P13945 1/20 0.37
HCRTR2 O43614 1/20 0.36
F2 P00734 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA9 Q16790 1/20 0.34
STAT5B P51692 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
MGAT3 Q09327 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803479 0.86 PTPRB (0.45) PTGER2
SCHEMBL6799662 0.86 MMP1 (0.47)
SCHEMBL6803115 0.82 KCNA5 (0.41) PTGER2TAS2R14ADRB3HCRTR2
SCHEMBL7067656 0.81 STAT5B (0.44) TAS2R14ADRB3F2CA12CA1
SCHEMBL22516852 0.73 PHLPP2 (0.40) ADRB3F2CA12CA1CA2
SCHEMBL5280924 0.72 LTB4R (0.51) CA1CA2CA9
SCHEMBL6800867 0.72 MMP1 (0.43)
SCHEMBL18067949 0.71 ADRB3 (0.46) ADRB3
SCHEMBL22567698 0.71 STAT5B (0.41) TAS2R14F2CA12CA1CA2
SCHEMBL18067959 0.70 ADRB3 (0.45) ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE PTGER2 3225/4885TAS2R14 3019/4885ADRB3 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.