SCHEMBL6926342

SCHEMBL6926342

Cc1ccc(S(=O)(=O)N(CCc2ccc(OS(N)(=O)=O)cc2)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
STAT5B P51692 2/20 0.44
CA12 O43570 2/20 0.43
CNR2 P34972 2/20 0.41
F2 P00734 1/20 0.41
CA4 P22748 1/20 0.41
TP53 P04637 1/20 0.41
STAT3 P40763 1/20 0.40
BMP1 P13497 2/20 0.39
PPARG P37231 1/20 0.39
STS P08842 3/20 0.38
ENPP1 P22413 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067656 0.87 STAT5B (0.44) CA1CA2CA9STAT5BCA12
SCHEMBL6802678 0.82 BMP1 (0.46) CA1CA2CA9STAT5BCA12
SCHEMBL6796826 0.81 PTPRB (0.45) STAT5BCNR2TP53ALDH1A1MAPT
SCHEMBL6803486 0.81 TP53 (0.47) CA1CA2CA9CA12CNR2
SCHEMBL7063146 0.80 STAT5B (0.47) CA1CA2CA9STAT5BCA12
SCHEMBL20983530 0.78 BMP1 (0.51) CA1CA2CA9STAT5BCA12
SCHEMBL14327847 0.77 STAT5B (0.49) CA1CA2CA9STAT5BCA12
SCHEMBL14327849 0.77 STAT5B (0.48) CA1CA2CA9STAT5BCA12
SCHEMBL5280924 0.75 LTB4R (0.51) CA1CA2CA9LMNAMAPT
SCHEMBL9181881 0.75 STAT5B (0.45) CA2CA9STAT5BCA12CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed