Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963969 | 0.83 | CYP2D6 (0.51) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL7069407 | 0.80 | LMNA (0.47) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL28048222 | 0.79 | LMNA (0.51) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL203531 | 0.76 | CYP1A2 (0.48) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL28327322 | 0.76 | CYP2D6 (0.51) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL9928673 | 0.76 | TSHR (0.52) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL18489548 | 0.74 | MAPK1 (0.57) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL1784572 | 0.74 | CYP1A2 (0.49) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL1783478 | 0.74 | CYP2D6 (0.52) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 | |
| SCHEMBL1787931 | 0.73 | MAPK1 (0.71) | TSHRCYP2D6CYP1A2CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891988-B1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE SPA (IT) | 2003-06-04 | — | — | EP | disclosed |
| EP-0451645-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-05-12 | — | — | EP | disclosed |
| EP-0891988-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5068213-A | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | HINMONT INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0451645-A2 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1991-10-16 | — | — | EP | disclosed |