Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067775 | 0.90 | UTS2R (0.42) | UTS2RHTR7ESR1ABCB1CYP3A4 | |
| SCHEMBL6817279 | 0.84 | UTS2R (0.42) | UTS2RHTR7ESR1ABCB1CYP3A4 | |
| SCHEMBL6820268 | 0.80 | UTS2R (0.42) | UTS2RHTR7ESR1ABCB1CYP3A4 | |
| SCHEMBL6917789 | 0.78 | MEN1 (0.35) | ABCB1CYP3A4ALDH1A1DNM1MAPT | |
| SCHEMBL3559402 | 0.77 | HTR6 (0.39) | HTR7ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL3561464 | 0.77 | ALDH1A1 (0.45) | HTR7ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL6917019 | 0.77 | ESR1 (0.48) | HTR7ESR1ALDH1A1KDM4EMAPT | |
| SCHEMBL6820218 | 0.76 | UTS2R (0.44) | UTS2RHTR7ESR1ALDH1A1KDM4E | |
| SCHEMBL3565558 | 0.76 | HTR6 (0.46) | HTR7ALDH1A1KDM4ELMNADRD2 | |
| SCHEMBL6820229 | 0.76 | ALDH1A1 (0.43) | HTR7ABCB1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |