SCHEMBL7068256

SCHEMBL7068256

OCCCc1ccc2nc3ccccc3nc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.46
PDE3A Q14432 2/20 0.46
P2RY12 Q9H244 2/20 0.46
NQO2 P16083 5/20 0.43
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
POLB P06746 3/20 0.41
RAD52 P43351 1/20 0.41
LTA4H P09960 1/20 0.41
EPHX2 P34913 1/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 3/20 0.41
NPC1 O15118 3/20 0.41
KMT2A Q03164 3/20 0.41
USP2 O75604 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PSMB5 P28074 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416607 0.89 NQO2 (0.46) NQO2ALDH1A1LMNAHPGDPOLB
SCHEMBL7073871 0.81 PSMB5 (0.54) NQO2ALDH1A1LMNAHPGDPOLB
SCHEMBL3610084 0.76 KDM4E (0.45) PDE3BPDE3AP2RY12ALDH1A1LTA4H
SCHEMBL13156595 0.75 PDE3B (0.51) PDE3BPDE3AP2RY12NQO2ALDH1A1
SCHEMBL81147 0.75 CYP1A2 (0.62) LTA4HEPHX2CYP1A2
SCHEMBL31265269 0.75 CYP1A2 (0.62) LTA4HEPHX2CYP1A2
SCHEMBL6360170 0.74 ALDH1A1 (0.51) PDE3BPDE3AP2RY12ALDH1A1LTA4H
SCHEMBL3158800 0.74 DAO (0.51) PDE3BPDE3AP2RY12ALDH1A1POLB
SCHEMBL9670577 0.73 CYP1A2 (0.50) PDE3BPDE3AP2RY12ALDH1A1LTA4H
SCHEMBL5656105 0.73 CYP1A2 (0.55) ALDH1A1HPGDLTA4HEPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed