SCHEMBL7073871

SCHEMBL7073871

CCCCc1ccc2nc3ccccc3nc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 2/20 0.54
NQO2 P16083 4/20 0.47
TLR8 Q9NR97 4/20 0.46
DHODH Q02127 1/20 0.46
ALDH1A1 P00352 3/20 0.45
LMNA P02545 3/20 0.45
HPGD P15428 2/20 0.45
SKP2 Q13309 1/20 0.44
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
HSD11B1 P28845 1/20 0.42
ATP4A P20648 1/20 0.42
ATP4B P51164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13156563 0.85 TLR8 (0.51) TLR8ALDH1A1LMNAKDM4EHIF1A
SCHEMBL23130637 0.85 PSMB5 (0.57) PSMB5TLR8LMNAHPGDSKP2
Phenazine SCHEMBL28800562 0.82 KDM4E (0.52) PSMB5TLR8DHODHALDH1A1LMNA
SCHEMBL18805360 0.81 TLR8 (0.51) TLR8ALDH1A1LMNAKDM4EHIF1A
SCHEMBL7068256 0.81 PDE3B (0.46) PSMB5NQO2ALDH1A1LMNAHPGD
SCHEMBL4371752 0.80 NQO2 (0.54) NQO2ALDH1A1LMNAHPGDKDM4E
SCHEMBL19478673 0.80 PSMB5 (0.52) PSMB5TLR8ALDH1A1LMNASKP2
SCHEMBL28107454 0.79 MAOA (0.53) PSMB5TLR8DHODHALDH1A1HPGD
SCHEMBL11688029 0.78 TLR8 (0.56) TLR8ALDH1A1HPGDTRPV1
SCHEMBL29416607 0.77 NQO2 (0.46) NQO2ALDH1A1LMNAHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed