Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563678 | 0.70 | HSP90AA1 (0.43) | LMNAHTR2A | |
| SCHEMBL6830687 | 0.68 | HTR6 (0.57) | POLBHTR6 | |
| SCHEMBL3563271 | 0.67 | CA12 (0.56) | CA12CA9CA2HTR6RECQL | |
| SCHEMBL6829881 | 0.67 | SLC2A1 (0.56) | POLBHTR6ALDH1A1LMNAMAPT | |
| SCHEMBL369194 | 0.66 | CA12 (0.52) | POLBCA12CA9CA2HTR6 | |
| SCHEMBL30276218 | 0.66 | CA12 (0.52) | POLBCA12CA9CA2HTR6 | |
| SCHEMBL13801415 | 0.66 | CA12 (0.40) | CA12CA9CA2HTR6RECQL | |
| SCHEMBL28059442 | 0.66 | CA12 (0.55) | CA12CA9CA2HTR6RECQL | |
| SCHEMBL28411710 | 0.65 | NOD1 (0.53) | POLBCA12CA9CA2HTR6 | |
| SCHEMBL6864954 | 0.65 | CA12 (0.54) | POLBCA12CA9CA2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |