Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 4/20 | 0.43 |
| ▸ | CHUK | O15111 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3927795 | 0.85 | CLCN2 (0.54) | BCAT2CLCN2PDK2KDM4ETSHR | |
| SCHEMBL27996934 | 0.82 | CCNC (0.55) | CASP1IKBKBCHUKIKBKEPKMYT1 | |
| SCHEMBL811777 | 0.79 | KMT2A (0.52) | BCAT2CASP1KMT2AATMKDM4E | |
| SCHEMBL4030359 | 0.78 | BCAT2 (0.63) | BCAT2CASP1IKBKBCHUKIKBKE | |
| SCHEMBL6255108 | 0.77 | SLC6A3 (0.55) | KMT2ACLCN2PDK2KDM4EMEN1 | |
| SCHEMBL8885349 | 0.76 | KMT2A (0.53) | BCAT2CASP1KMT2AATMCLCN2 | |
| SCHEMBL17609420 | 0.76 | BCAT2 (0.61) | BCAT2CASP1KMT2AATMIKBKB | |
| SCHEMBL656983 | 0.76 | BCAT2 (0.88) | BCAT2CASP1KMT2AIKBKBCHUK | |
| SCHEMBL29032707 | 0.76 | BCAT2 (0.60) | BCAT2CASP1KMT2AIKBKBCHUK | |
| SCHEMBL28159776 | 0.76 | BCAT2 (0.60) | BCAT2CASP1KMT2AIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140072-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2003-04-16 | — | — | EP | claimed |
| EP-1140072-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040239-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-13 | — | — | WO | claimed |