Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | CCR1 | P32246 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511865 | 0.94 | DRD4 (0.49) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7508560 | 0.91 | DRD4 (0.57) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7512915 | 0.91 | DRD4 (0.57) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7508179 | 0.90 | HRH1 (0.63) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7507212 | 0.88 | DRD2 (0.51) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7513106 | 0.86 | DRD4 (0.50) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7511059 | 0.86 | DRD4 (0.50) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL6214454 | 0.85 | DRD4 (0.53) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7512148 | 0.85 | HRH1 (0.57) | DRD4DRD2DRD3HRH1CCR3 | |
| SCHEMBL7509383 | 0.83 | DRD2 (0.45) | DRD4DRD2DRD3HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030149047-A1 | Novel compounds | ASTRAZENCA AB (SE) | 2003-08-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149047-A1 | Novel compounds | RPS4Y1, RPS4X, RPS6 | DRD4 433/4885DRD2 879/4885DRD3 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.