SCHEMBL7069246

SCHEMBL7069246

COc1ccc(N(c2ccccc2)S(=O)(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
PGR P06401 1/20 0.49
KMT2A Q03164 3/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
TRPM8 Q7Z2W7 2/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
CA4 P22748 1/20 0.45
HSP90AA1 P07900 1/20 0.45
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
F2 P00734 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565624 0.84 RAB9A (0.52) KDM4EHPGDKMT2ACES2CES1
SCHEMBL450584 0.82 ESR1 (0.52) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL31190140 0.81 CNR1 (0.49) KDM4EHPGDPGRKMT2AMTNR1A
SCHEMBL11322994 0.80 ESR1 (0.50) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL378351 0.80 ESR1 (0.50) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL11308673 0.80 ESR1 (0.50) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL415688 0.80 ESR1 (0.50) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL28182966 0.80 ESR1 (0.50) HPGDKMT2AHSP90AA1ALDH1A1TSHR
SCHEMBL7074889 0.79 ALDH1A1 (0.51) HPGDKMT2AL3MBTL1CES2CES1
SCHEMBL8924255 0.79 PKM (0.50) KDM4EHPGDPGRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090962-B1 Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-05-14 EP disclosed
EP-1090962-A2 Dye mixtures of fiber-reactive azo dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-04-11 EP disclosed