SCHEMBL7069267

SCHEMBL7069267

CN=C1CC=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
SETD7 Q8WTS6 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
ABCB11 O95342 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRM5 P08912 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
TSHR P16473 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM3 P20309 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069264 1.00 ALDH1A1 (0.33) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19
SCHEMBL7886467 0.80 HPGD (0.40) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19
SCHEMBL7886462 0.80 HPGD (0.40) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19
SCHEMBL9435237 0.79 MAPT (0.32) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19
SCHEMBL7866209 0.77 CYP2D6 (0.34) ALDH1A1HSD17B10CYP2D6CYP2C19MEN1
SCHEMBL7866217 0.77 CYP2D6 (0.34) ALDH1A1HSD17B10CYP2D6CYP2C19MEN1
SCHEMBL28634060 0.73 ALDH1A1 (0.36) ALDH1A1HSD17B10MEN1LMNAMAPT
SCHEMBL219752 0.72 TSHR (0.36) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19
SCHEMBL3401294 0.72 NPC1 (0.38) ALDH1A1TP53HTTMEN1LMNA
SCHEMBL7214854 0.72 ALDH1A1 (0.38) ALDH1A1HSD17B10SETD7CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105934510-B Photoactivators 宝洁公司 2020-07-24 CN disclosed
CN-1860107-B Methods for the preparation of benzoxazole sulfonamide compounds and intermediates thereof TIBOTEC PHARM LTD 2013-08-21 CN disclosed
CN-1938316-B Methods for the preparation of (3r,3as,6ar) hexahydro-furo[2,3-b]furan-3-ol TIBOTEC PHARM LTD 2012-12-12 CN disclosed
CN-1938316-A Methods for the preparation of (3r,3as,6ar) hexahydro-furo[2,3-b]furan-3-ol TIBOTEC PHARM LTD (IE) 2007-03-28 CN disclosed
CN-1860107-A Methods for the preparation of benzoxazole sulfonamide compounds and intermediates thereof TIBOTEC PHARM LTD (IE) 2006-11-08 CN disclosed
EP-0894825-B1 DIENE POLYMER COMPOSITION, PROCESS FOR THE PREPARATION OF THE SAME, AND RUBBER COMPOSITION CONTAINING THE SAME NIPPON ZEON CO (JP) 2003-07-23 EP disclosed
CN-1432014-A Triazole compound of amide series SANKYO CO (JP) 2003-07-23 CN disclosed
EP-0894824-B1 RUBBER COMPOSITION NIPPON ZEON CO (JP) 2003-06-18 EP disclosed
EP-0882738-B1 DIENE RUBBER, PROCESS FOR PRODUCING THE RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME ZEON CORP (JP) 2002-11-20 EP disclosed
EP-0864606-B1 RUBBER COMPOSITION ZEON CORP (JP) 2002-06-05 EP disclosed
EP-0864606-A1 RUBBER COMPOSITION NIPPON ZEON CO., LTD. (JP) 1998-09-16 EP disclosed
EP-0639587-B1 Diene polymers and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents BRIDGESTONE FIRESTONE INC (US) 1997-10-22 EP disclosed
EP-0510410-B1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE FIRESTONE INC (US) 1996-06-12 EP disclosed
EP-0639587-A1 Diene polymeres and copolymers terminated with compounds having multiple-bonded nitrogen atoms and partially crosslinked with polyfunctional reagents BRIDGESTONE/FIRESTONE, INC. (US) 1995-02-22 EP disclosed
EP-0451604-B1 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE FIRESTONE INC (US) 1994-12-21 EP disclosed
US-5227431-A DIENE POLYMERS AND COPOLYMERS JUMPED BY PARTIAL CROSSLINKING AND TERMINATED WITH A SUBSTITUTED IMINE BRIDGESTONE/FIRESTONE, INC. (US) 1993-07-13 US disclosed
EP-0510410-A1 Diene polymers and copolymers jumped by partial coupling and terminated with a substituted imine BRIDGESTONE/FIRESTONE, INC. (US) 1992-10-28 EP disclosed
US-5109907-A Tire treads with reduced rolling resistance BRIDGESTONE/FIRESTONE, INC. (US) 1992-05-05 US disclosed
US-5066729-A Tire Treads BRIDGESTONE/FIRESTONE, INC. (US) 1991-11-19 US disclosed
EP-0451604-A2 Diene polymers and copolymers terminated by reaction with n-alkyl and n-aryl imines BRIDGESTONE/FIRESTONE, INC. (US) 1991-10-16 EP disclosed