O-Xylene

O-Xylene

SCHEMBL7069414

CC(=O)CC(C)C.Cc1ccccc1C

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
ACHE P22303 2/20 0.43
TSHR P16473 2/20 0.43
F2R P25116 1/20 0.43
SLC25A5 P05141 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
P2RX7 Q99572 1/20 0.41
HPGD P15428 3/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 2/20 0.40
HTT P42858 1/20 0.40
GAA P10253 1/20 0.39
ANPEP P15144 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL9644431 0.88 ALDH1A1 (0.47) ALDH1A1TDP1ACHETSHRF2R
O-Tolylamine SCHEMBL8523423 0.87 TDP1 (0.52) ALDH1A1TDP1ACHEF2RSLC25A5
O-Xylene SCHEMBL11230054 0.86 ALDH1A1 (0.45) ALDH1A1TDP1TSHRF2RSLC25A5
O-Xylene SCHEMBL9439330 0.86 TDP1 (0.45) ALDH1A1TDP1ACHETSHRF2R
Methyl Isobutyl Ketone SCHEMBL163328 0.85 ALDH1A1 (0.58) ALDH1A1TDP1ACHETSHRSLC25A5
O-Xylene SCHEMBL10819029 0.84 ACHE (0.55) ALDH1A1TDP1ACHETSHRF2R
P-Xylene SCHEMBL27317096 0.82 TDP1 (0.67) ALDH1A1TDP1ACHESLC25A5SMN1; SMN2
Methyl Isobutyl Ketone SCHEMBL9328768 0.82 ALDH1A1 (0.54) ALDH1A1TDP1ACHETSHRSLC25A5
Acetic Acid Butyl Ester SCHEMBL5411321 0.81 ALDH1A1 (0.51) ALDH1A1TDP1TSHRSMN1; SMN2HPGD
Methyl Isobutyl Ketone SCHEMBL7048520 0.81 ALDH1A1 (0.82) ALDH1A1TDP1SLC25A5SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003046048-A1 PROCESS FOR ALKYLATION OF AN ALKOXYLATED MONO DI, TRI OR POLYHYDRIC COMPOUND PERSTORP SPECIALTY CHEMICALS AB (SE) 2003-06-05 WO claimed
JP-7039511-A None JP disclosed
CN-104784811-B Flexible tube, endoscopic medical device, and resin composition for top coat layer 富士胶片株式会社 2020-03-24 CN disclosed
CN-110361942-A Electrophtography photosensor, handle box, image forming apparatus and imide compound 富士施乐株式会社 2019-10-22 CN disclosed
CN-103309182-B Electrophtography photosensor, handle box, image forming apparatus and image forming method 富士施乐株式会社 2018-10-09 CN disclosed
CN-103365130-B Electrophtography photosensor, image forming apparatus and handle box 富士施乐株式会社 2018-10-09 CN disclosed
CN-103365126-B Electrophtography photosensor, image forming apparatus and handle box 富士施乐株式会社 2018-05-25 CN disclosed
CN-103105755-B Imaging device 富士施乐株式会社 2017-06-16 CN disclosed
CN-102998920-B Electrophtography photosensor and its manufacture method, image forming apparatus and handle box 富士施乐株式会社 2017-06-09 CN disclosed
CN-106556989-A Charging unit, handle box and image processing system 富士施乐株式会社 2017-04-05 CN disclosed
US-4857567-A CORROSION RESISTANCE BASF CORPORATION, INMONT DIVISION (US) 1989-08-15 US disclosed
EP-0300504-A2 Principal resin emulsions for electrodeposition coatings. BASF Corporation (US) 1989-01-25 EP disclosed
US-4755418-A Preventing yellowing by depositing primer coating containing amine-epoxy resin and blocked polyisocyanate crosslinking agent BASF CORPORATION (US) 1988-07-05 US disclosed
EP-0265363-A2 Nonyellowing cathodic electrocoat BASF CORPORATION (US) 1988-04-27 EP disclosed
EP-0201444-A1 Low volatile organic content cathodic electrodeposition baths BASF Corporation (US) 1986-11-12 EP disclosed
EP-0198783-A2 Alkanolamine hydroxy-capped epoxy for cathodic electrocoat BASF Corporation (US) 1986-10-22 EP disclosed
US-4605690-A Low volatile organic content cathodic electrodeposition baths INMONT CORPORATION (US) 1986-08-12 US disclosed
EP-0189728-A2 Oxime blocked isocyanate cross-linker for cathodic electrocoat BASF CORPORATION (US) 1986-08-06 EP disclosed
US-4596842-A Alkanolamine hydroxy-capped epoxy for cathodic electrocoat INMONT CORPORATION (US) 1986-06-24 US disclosed
US-4596744-A Oxime blocked isocyanate cross-linker for cathodic electrocoat INMONT CORPORATION (US) 1986-06-24 US disclosed