Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070039 | 0.87 | PPARA (0.40) | SGMS2PPARAPPARGPPARD | |
| SCHEMBL7068859 | 0.87 | PPARA (0.35) | PPARAPPARGPPARD | |
| SCHEMBL7069480 | 0.87 | PPARA (0.50) | PPARAPPARGPPARDMAOB | |
| SCHEMBL7069293 | 0.84 | HTR1A (0.35) | PPARAPPARGPPARDMAOBALDH1A1 | |
| SCHEMBL7068137 | 0.84 | FFAR4 (0.36) | PPARAPPARGPPARD | |
| SCHEMBL7069562 | 0.81 | FFAR4 (0.40) | PPARAPPARGPPARD | |
| SCHEMBL7067931 | 0.80 | NUDT1 (0.39) | PPARAPPARGPPARD | |
| SCHEMBL7072401 | 0.80 | PPARA (0.39) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL7072687 | 0.79 | PPARA (0.39) | PPARAPPARGPPARDCYP2C9 | |
| SCHEMBL7070148 | 0.79 | MAPT (0.38) | PPARAPPARGPPARDALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | SGMS2 4072/4885S1PR1 4417/4885CYP2D6 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.