Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 13/20 | 0.35 |
| ▸ | PPARA | Q07869 | 12/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072057 | 0.93 | FFAR4 (0.38) | FFAR4FFAR1PTGDR2 | |
| SCHEMBL7068137 | 0.87 | FFAR4 (0.36) | FFAR4PPARGPPARAPPARDFFAR1 | |
| SCHEMBL7070148 | 0.85 | MAPT (0.38) | FFAR4PPARGPPARAPPARDFFAR1 | |
| SCHEMBL7069559 | 0.85 | PPARA (0.53) | PPARGPPARAPPARD | |
| SCHEMBL7067931 | 0.83 | NUDT1 (0.39) | FFAR4PPARGPPARAPPARD | |
| SCHEMBL7070039 | 0.83 | PPARA (0.40) | PPARGPPARAPPARDSLC1A5 | |
| SCHEMBL7068859 | 0.83 | PPARA (0.35) | PPARGPPARAPPARDSLC1A5 | |
| SCHEMBL7072401 | 0.83 | PPARA (0.39) | PPARGPPARAPPARDPTGDR2 | |
| SCHEMBL7072687 | 0.82 | PPARA (0.39) | PPARGPPARAPPARD | |
| SCHEMBL7069484 | 0.81 | SGMS2 (0.35) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | MITSUI CHEMICALS, INC. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212100-A1 | Quinoline derivatives and medicinal use thereof | PPARG, PPARD, PPARA | FFAR4 734/4885PPARG 1/4885PPARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.