Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832494 | 0.94 | CA12 (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL6834536 | 0.92 | STS (0.39) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL5160647 | 0.91 | HTR1A (0.39) | KMT2APPARAHSD17B10STS | |
| SCHEMBL6829427 | 0.91 | MTNR1A (0.43) | CA1CA2CA9KMT2APPARA | |
| Water SCHEMBL5161066 | 0.90 | HTR1A (0.38) | KMT2APPARAHSD17B10STS | |
| SCHEMBL6832568 | 0.87 | ENPP1 (0.44) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL4797598 | 0.85 | CA12 (0.40) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL6832979 | 0.83 | STS (0.40) | STS | |
| SCHEMBL2686642 | 0.83 | PPARA (0.52) | CA12CA1CA2CA9PPARA | |
| SCHEMBL6829303 | 0.83 | PPARA (0.40) | KMT2APPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |