Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829303 | 0.92 | PPARA (0.40) | MTNR1AMTNR1BKMT2APPARAPPARG | |
| SCHEMBL7069550 | 0.91 | CA12 (0.40) | KMT2ACA1CA2CA9PPARA | |
| SCHEMBL6832494 | 0.85 | CA12 (0.41) | KMT2ACA1CA2CA9PPARA | |
| SCHEMBL6832055 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6834536 | 0.83 | STS (0.39) | KMT2ACA1CA2CA9PPARA | |
| Water SCHEMBL5161066 | 0.81 | HTR1A (0.38) | MTNR1AMTNR1BKMT2APPARA | |
| SCHEMBL6832568 | 0.79 | ENPP1 (0.44) | KMT2ACA1CA2CA9PPARG | |
| SCHEMBL6566136 | 0.77 | ACHE (0.38) | MTNR1BPPARAPPARGPTPN1 | |
| SCHEMBL4797598 | 0.76 | CA12 (0.40) | KMT2ACA1CA2CA9PPARA | |
| SCHEMBL6832979 | 0.74 | STS (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |