SCHEMBL707004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707999	0.87	LMNA (0.56)	KMT2AMEN1SMN1; SMN2CYP2C19GPR119
	SCHEMBL28008432	0.86	SMN1; SMN2 (0.50)	KMT2AMEN1SMN1; SMN2CYP2C19GPR119
	SCHEMBL2773033	0.84	PARP1 (0.50)	KMT2AHTTNPSR1LMNAPARP1
	SCHEMBL1160490	0.83	PARP1 (0.49)	KMT2ASMN1; SMN2HTTPARP1TNK2
	SCHEMBL30414220	0.83	LMNA (0.49)	KMT2AMEN1SMN1; SMN2CYP2C19HTT
	SCHEMBL1479509	0.83	LMNA (0.49)	KMT2AMEN1SMN1; SMN2CYP2C19HTT
	SCHEMBL710576	0.83	LMNA (0.53)	KMT2AMEN1SMN1; SMN2CYP2C19LMNA
	SCHEMBL25403748	0.83	L3MBTL1 (0.57)	KMT2AMEN1SMN1; SMN2CYP2C19GPR119
	SCHEMBL532058	0.83	POLB (0.49)	KMT2AMEN1SMN1; SMN2CYP2C19GPR119
	SCHEMBL24670700	0.81	MAPT (0.62)	KMT2AMEN1SMN1; SMN2CYP2C19GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.