Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070205 | 1.00 | ESR1 (0.54) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL19073839 | 0.82 | ALDH1A1 (0.41) | MAPTHTTLMNAMEN1CYP3A4 | |
| SCHEMBL19963519 | 0.80 | CYP19A1 (0.45) | ESR1ESR2MAPTHSD17B10LMNA | |
| SCHEMBL19836782 | 0.76 | HTT (0.40) | MAPTHTTLMNAMEN1KMT2A | |
| SCHEMBL9335607 | 0.76 | NR4A1 (0.61) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL7931944 | 0.75 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL13841246 | 0.75 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL4366150 | 0.75 | ESR1 (0.62) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL17681905 | 0.74 | DEGS1 (0.42) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL14035623 | 0.73 | ESR1 (0.54) | ESR1ESR2PTGS1PTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114716-A1 | Method of producing bisphenol-A | JACKSON BARRIE W (CA) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114716-A1 | Method of producing bisphenol-A | ADH1A, ADH1C, EBP | ESR1 81/4885ESR2 154/4885PTGS1 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.