Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | ADK | P55263 | 11/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070066 | 0.89 | ADK (0.79) | HTR2BSIGMAR1ADRA2COPRK1HTR6 | |
| SCHEMBL17800845 | 0.87 | ADK (0.66) | ADKTP53ADORA3SLC29A1PAX8 | |
| SCHEMBL8331212 | 0.84 | ADK (0.71) | HTR2BSIGMAR1ADRA2COPRK1HTR6 | |
| SCHEMBL8332977 | 0.82 | ADORA3 (0.69) | HTR2BSIGMAR1ADRA2COPRK1HTR6 | |
| SCHEMBL16968462 | 0.82 | DOT1L (0.71) | ADKTP53TDP1PAX8 | |
| SCHEMBL6838180 | 0.82 | ADK (0.72) | ADKTP53SLC29A1TDP1 | |
| SCHEMBL6426263 | 0.82 | DOT1L (0.71) | ADKTP53TDP1PAX8 | |
| SCHEMBL13092047 | 0.82 | DOT1L (0.71) | ADKTP53TDP1PAX8 | |
| SCHEMBL16978208 | 0.82 | DOT1L (0.71) | ADKTP53TDP1PAX8 | |
| SCHEMBL17800867 | 0.82 | ADK (0.67) | ADKTP53SLC29A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051899-A1 | DEAZAPURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |