Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.69 |
| ▸ | ADK | P55263 | 13/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070066 | 0.92 | ADK (0.79) | ADORA3ADKSIGMAR1HTR2BADRA2C | |
| SCHEMBL8331212 | 0.91 | ADK (0.71) | ADORA3ADKSIGMAR1HTR2BADRA2C | |
| SCHEMBL8975497 | 0.88 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADKSIGMAR1 | |
| SCHEMBL8333099 | 0.86 | ADK (0.84) | ADK | |
| SCHEMBL8333496 | 0.85 | ADK (0.71) | ADKSIGMAR1HTR2BADRA2COPRK1 | |
| SCHEMBL8975415 | 0.84 | ADK (0.68) | ADORA3ADORA2AADORA1ADKSIGMAR1 | |
| SCHEMBL7070318 | 0.82 | HTR2B (0.69) | ADORA3ADKSIGMAR1HTR2BADRA2C | |
| SCHEMBL17800859 | 0.82 | ADK (0.80) | ADK | |
| SCHEMBL8330336 | 0.81 | ADK (0.89) | ADK | |
| SCHEMBL6762195 | 0.81 | ADORA3 (1.00) | ADORA3ADORA2AADORA1TP53SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684953-A4 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES. | GENSIA INC (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |
| EP-0684953-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018215-A1 | ADENOSINE KINASE INHIBITORS COMPRISING LYXOFURANOSYL DERIVATIVES | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |