SCHEMBL7070602

SCHEMBL7070602

CCCCCOC1C=CC2C3C=CC(C3)C12

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.36
ALDH1A1 P00352 1/20 0.32
PPARG P37231 2/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18789885 0.98 GBA1 (0.39) GBA1ALDH1A1PPARGPPARDPPARA
SCHEMBL10401725 0.98 GBA1 (0.39) GBA1ALDH1A1PPARGPPARDPPARA
SCHEMBL22738801 0.95 GBA1 (0.30) GBA1
SCHEMBL18789886 0.88
SCHEMBL22263641 0.68 GBA1 (0.47) GBA1ALDH1A1
SCHEMBL16254136 0.68 GBA1 (0.43) GBA1ALDH1A1PPARGPPARDPPARA
SCHEMBL7165503 0.65 GBA1 (0.47) GBA1ALDH1A1PPARGPPARD
SCHEMBL12228730 0.65 GBA1 (0.39) GBA1ALDH1A1
SCHEMBL17203503 0.63 ALDH1A1 (0.47) GBA1ALDH1A1
SCHEMBL4783622 0.63 GBA1 (0.42) GBA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1208070-A4 DIOLEFIN/HYDROXYARYL CONDENSATES AND CATALYST THEREFOR BORDEN CHEM INC (US) 2003-10-15 EP disclosed
EP-1208070-A1 DIOLEFIN/HYDROXYARYL CONDENSATES AND CATALYST THEREFOR BORDEN CHEMICAL, INC. (US) 2002-05-29 EP disclosed
US-6291723-B1 Diolefin/hydroxyaryl condensates and catalyst therefor BORDEN CHEMICAL, INC. 2001-09-18 US disclosed
WO-2001016064-A1 DIOLEFIN/HYDROXYARYL CONDENSATES AND CATALYST THEREFOR BORDEN CHEMICAL, INC. (US) 2001-03-08 WO disclosed