Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070676 | 1.00 | MTNR1A (0.48) | MTNR1AMTNR1BLMNAPKMHTT | |
| SCHEMBL8261373 | 0.81 | MAOB (0.57) | MTNR1AMTNR1BMAOBPPARG | |
| SCHEMBL5152333 | 0.81 | MAOB (0.57) | MTNR1AMTNR1BMAOBPPARG | |
| SCHEMBL7070509 | 0.77 | MAPT (0.48) | MTNR1AMTNR1BLMNAMAOB | |
| SCHEMBL7070513 | 0.77 | MAPT (0.48) | MTNR1AMTNR1BLMNAMAOB | |
| SCHEMBL7070372 | 0.76 | SRR (0.40) | PKMPPARGPPARA | |
| SCHEMBL7070367 | 0.76 | SRR (0.40) | PKMPPARGPPARA | |
| Hydrochloric Acid SCHEMBL7070234 | 0.74 | PPARG (0.45) | HTTPPARGPPARA | |
| Hydrochloric Acid SCHEMBL7070231 | 0.74 | PPARG (0.45) | HTTPPARGPPARA | |
| SCHEMBL9318626 | 0.72 | MAPT (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142865-B1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6395932-B1 | AMINOALKYL-1,2-DIPHENYL-2-PROPEN-1-ONE WHICH LOWER INTRAOCULAR PRESSURE BY CAUSING MORPHOLOGICAL CHANGE IN TRABECULAR MESHWORK CELLS. | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |