Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070367 | 1.00 | SRR (0.40) | SRRPPARGPPARAHTR2AEPHX1 | |
| Hydrochloric Acid SCHEMBL7070234 | 0.79 | PPARG (0.45) | PPARGPPARAAOC3 | |
| Hydrochloric Acid SCHEMBL7070231 | 0.79 | PPARG (0.45) | PPARGPPARAAOC3 | |
| SCHEMBL6201202 | 0.76 | ALDH1A1 (0.46) | SRRPPARGPPARAEPHX1ALPI | |
| SCHEMBL7070679 | 0.76 | MTNR1A (0.48) | PPARGPPARAPKM | |
| SCHEMBL7070676 | 0.76 | MTNR1A (0.48) | PPARGPPARAPKM | |
| SCHEMBL125923 | 0.74 | LMNA (0.58) | EPHX1AOC3 | |
| SCHEMBL460826 | 0.74 | IDO1 (0.58) | HTR2AIDO1PAMAOC3 | |
| SCHEMBL10422962 | 0.74 | IDO1 (0.58) | HTR2AIDO1PAMAOC3 | |
| SCHEMBL4355212 | 0.74 | LMNA (0.58) | EPHX1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142865-B1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6395932-B1 | AMINOALKYL-1,2-DIPHENYL-2-PROPEN-1-ONE WHICH LOWER INTRAOCULAR PRESSURE BY CAUSING MORPHOLOGICAL CHANGE IN TRABECULAR MESHWORK CELLS. | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |